MST43

Name: George W YIP 

Title: Associate Professor 

Office Mailing Address: Department of Anatomy, Yong Loo Lin School of Medicine, National  University of Singapore, 4 Medical Drive, Block MD 10, Singapore 117594 

E-mail: georgeyip@nus.edu.sg 

Telephone Number: (+65) 6516 3206 

Current Positions:  1. Associate Professor, Department of Anatomy, Yong Loo Lin School of Medicine, National  University of Singapore  2. Head, Department of Anatomy, Yong Loo Lin School of Medicine, National University of  Singapore 

Academic Qualifications:  1. Bachelor of Medicine, Bachelor of Surgery (MBBS), National University of Singapore  2. Doctor of Philosophy (PhD), University College London 

Teaching Experience: I have been teaching Gross Anatomy, Embryology and Histology to medical  and dental students in the National University of Singapore since 1996. This includes large-group  teaching via lectures, and small-group teaching in practical classes and tutorials. I am involved in  developing new teaching materials and digital tools for anatomy education, including e-textbooks and  an anatomy chatbot. I am also a member of the Undergraduate Steering Committee, the Curriculum  Enhancement Taskforce, and the Curriculum Implementation Taskforce in the medical school.

Research Interests: My long-term research interest is in understanding the biological roles of  glycosaminoglycans and their downstream signalling pathways in cancer biology, with the objectives  of determining if these molecules could be used for predicting clinical outcome and development of  therapeutic targets. 

Selected Recent Publications:  1. Pang AS, Dinesh T, Pang NY, Dinesh V, Pang KY, Yong CL, Lee SJ, Yip GW, Bay BH,  Srinivasan DK. Nanoparticles as drug delivery systems for the targeted treatment of  atherosclerosis. Molecules. 2024. 29:2873.  2. Leong SX, Kao YC, Han X, Poh ZW, Chen JRT, Tan EX, Leong YX, Lee YH, Teo WX, Yip GW,  Lam Y, Ling XY. Achieving molecular recognition of structural analogues in surface-enhanced  Raman spectroscopy: Inducing charge and geometry complementarity to mimic molecular  docking. Angew Chem Int Ed Engl. 2023. 62:e202309610.  3. Masroni MSB, Lee KW, Lee VKM, Ng SB, Law CT, Poon KS, Lee BT, Liu Z, Tan YP, Chng WL,  Tucker S, Ngo LS, Yip GW, Nga ME, Hue SSS, Putti TC, Bay BH, Lin Q, Zhou L, Hartman M, Loh  TP, Lakshmanan M, Lee SY, Tergaonkar V, Chua H, Lee AVH, Yeo EYM, Li MH, Chang CF, Kee  Z, Tan KM, Tan SY, Koay ES, Archetti M, Leong SM. Dynamic altruistic cooperation within breast  tumors. Mol Cancer. 2023. 22:206.  4. Kamarudin JBM, Sun B, Foo ASC, Lim XY, Judd H, Tan X, Tan XH, Razar RBBA, Liu M, Zhong  J, Chua JJE, Ng CWQ, Goh JCH, Tan TZ, Parikh BH, Su X, Kumar AP, Ong WY, Yamaguchi N,  Set SY, Yip GW, Zhang Y, Teh DBL. SIRIUS, ultra-scintillating upconversion breast implant for  remote orthotopic photodynamic therapy. ACS Nano. 2023. 17:11593-11606.  5. Scully OJ, Shyamasundar S, Matsumoto K, Dheen ST, Yip GW, Bay BH. C1QBP mediates breast  cancer cell proliferation and growth via multiple potential signalling pathways. Int J Mol Sci. 2023.  24:1343.  6. Ibrahim SA, Yip GW, Gotte M. Cancer stem cells as attractive targets for breast cancer therapy.  Front Oncol. 2023. 13:1151742.  7. Parnigoni A, Caon I, Teo WX, Hua SH, Moretto P, Bartolini B, Viola M, Karousou E, Yip GW,  Gotte M, Heldin P, Passi A, Vigetti D. The natural antisense transcript HAS2-AS1 regulates breast  cancer cells aggressiveness independently from hyaluronan metabolism. Matrix Biol. 2022.  109:140-161.  8. Lucanus AJ, Thike AA, Tan XF, Lee KW, Guo S, King VPC, Yap VB, Bay BH, Tan PH, Yip GW.  KIF21A regulates breast cancer aggressiveness and is prognostic of patient survival and tumor  recurrence. Breast Cancer Res Treat. 2022. 191:63-75. 

Selected Awards:  1. A*STAR International Fellowship to Harvard University (2002 – 2003)  2. Japan Society for Promotion of Science Fellowship to Kobe Pharmaceutical University, Japan  (2005 and 2011)  3. NMRC Clinician Scientist Award (2013 and 2019)