The Microscopy Society of Thailand (MST)
Email: mstconference@gmail.com
The Microscopy Society of Thailand (MST)
MST43 Speaker Detail
SOONTAREE PETCHDEE, D.V.M., M.Sc., Ph.D., DAiCVIM (Cardiology)
Position Associate Professor
Department of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University,
Kamphaeng Saen Campus 73140, Thailand.
Tel: +6634-351901-3 ext 3450-1, +6682-7076905
Fax: +6634-351405
e-mail fvetstr@ku.ac.th
Education:
Bachelor: Doctor of Veterinary Medicine (honors), KhonKaen University, Thailand.
M.Sc. Physiology, Mahidol University, Thailand.
Ph.D. Cardiac Electrophysiology, University of Glasgow, United Kingdom.
Ph.D. thesis: Arrhythmia mechanisms in acute ischemia and chronic infarction in rabbit heart.
Soontaree Petchdee: Scopus ID: 14521566700; ORCID: 0000-0001-7552-937X.
Current affiliation: Faculty of Veterinary Medicine, Kasetsart University.
Academic degrees/training: PhD (Cardiac electrophysiology/Interventional Cardiology), University of Glasgow.
Academic title: Associate Professor
Research areas: Veterinary Medicine; Veterinary Cardiology; Cardiac electrophysiology; Translational cardioprotection; Diagnostic ultrasonography/echocardiography.
Author keywords: hypertrophic cardiomyopathy; echocardiography; mitral valve repair; cardioprotection; germinated brown rice; transcatheter edge-to-edge repair; veterinary cardiology; cardiac ischemia-reperfusion.
Professional biography: Dr. Soontaree Petchdee is an Associate Professor in the Faculty of Veterinary Medicine at Kasetsart University (Kamphaeng Saen campus). Her research focuses on veterinary cardiology, cardioprotection, diagnostic echocardiography, and translational cardiovascular models in small and large animals. She holds a PhD from the University of Glasgow and leads clinical and experimental projects, including work on mitral valve repair techniques in dogs and cardioprotective natural-product research.
Publications (2022–2025):
1. Sawatmongkol, N., Kalerum, P., Puncharoen, P., and Petchdee, S. (2025). Gastric Dilatation-Volvulus in a 2-Month-Old Puppy: A Case Report. Int. J. Vet. Sci., 14(6): 1368-1371. (Q2-Corresponding Author)
2. Weerakijpanich, W., and Petchdee S. (2025). The Evaluation and Management of Idiopathic Chylopericardium in a Cat: A Case Report. Int. J. Vet. Sci.,14(4): 815-819. (Q2-Corresponding Author)
3. Jaturanratsamee, K., Jiwaganont, P., Panprom, C., & Petchdee, S. (2024). Rivaroxaban versus enoxaparin plus clopidogrel therapy for hypertrophic cardiomyopathy-associated thromboembolism in cats. Veterinary world, 17(4), 796–803. https://doi.org/10.14202/vetworld.2024.796-803. (Q1-Corresponding Author)
4. Jiwaganont, P., Roytrakul, S., Thaisakun, S., Sukumolanan, P., & Petchdee, S. (2024). Investigation of coagulation and proteomics profiles in symptomatic feline hypertrophic cardiomyopathy and healthy control cats. BMC Veterinary Research, 20(1), 292. https://doi.org/10.1186/s12917-024-04170-0. (Q1-Corresponding Author)
5. Jiwaganont, P., Jaturanratsamee, K., Thaisakun, S., Roytrakul, S., & Petchdee, S. (2024). Analysis of serum proteomic in cats with polycystic kidney disease-1 gene mutation. Heliyon, 10(15), e35577. https://doi.org/10.1016/j.heliyon.2024.e35577. (Q1-Corresponding Author)
6. Demeekul, K., Sukumolanan, P., & Petchdee, S. (2024). Evaluation of galectin-3 and titin in cats with a sarcomeric gene mutation associated with echocardiography. Veterinary world, 17(10), 2407–2416. https://doi.org/10.14202/vetworld.2024.2407-2416. (Q1-Corresponding Author)
7. Panprom, C., Pattanapon, N., & Petchdee, S. (2024). The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats. Scientific reports, 14(1), 316. https://doi.org/10.1038/s41598-024-51162-z. (Q1-Corresponding Author)
8. Demeekul, K., Sukumolanan, P., Panprom, C., Thaisakun, S., Roytrakul, S., & Petchdee, S. (2022). Echocardiography and MALDI-TOF Identification of Myosin-Binding Protein C3 A74T Gene Mutations Involved Healthy and Mutated Bengal Cats. Animals, 12(14), 1782. https://doi.org/10.3390/ani12141782. (Q1-Corresponding Author)
9. Detcharoenyos, N., Silmaneephan, K., Lertchaiprasert, N., Petchdee, S. (2024). Management of Canine Spinal Cord Transmissible Venereal Tumor Int. J. Agric. Biosci, 13(3), 439–443. (Q1-Corresponding Author)
10. Petchdee, S., Pongkan, W., Lei, J., Jaturanratsamee, K., Bootcha, R., Meepoo, W., & Panprom, C. (2024). Transcatheter Edge-to-Edge Repair of the Mitral Valve in Four Dogs: Preliminary Results Regarding Efficacy and Safety. Animals. 14(21), 3068. https://doi.org/10.3390/ani14213068. (Q1-First and Corresponding Author)
11. Lertchaiprasert, N., Sawatmongkol, N., Kalerum, P., Tayayouth, S., Petchdee, S. (2023). The Successful Medical Treatment of Localized Tetanus in a Cat. Int. J. Vet. Sci., 13(2), 160–163. (Q2-Corresponding Author)
12. Panprom, C., Tayayouth, S., Pattanapon, N., Meepoo, W., Petchdee, S. (2023). The Evaluation and Management of Congenital Loss of the Pericardium in A Cat: A Case Report. Int. J. Vet. Sci., 12(5), 715-718. (Q2-Corresponding Author)
13. Jaturanratsamee, K., Jiwaganont, P., Sukumolanan, P., & Petchdee, S. (2023). PKD1 gene mutation and ultrasonographic characterization in cats with renal cysts. F1000Research, 12, 760. https://doi.org/10.12688/f1000research.134906.3. (Q1-Corresponding Author)
14. Panprom, C., Pattanapon, N., Meepoo, W., Petchdee, S. (2022). Anesthesia Consideration in a Dog with Degenerative Valve Disease Undergoing Soft Tissue Surgery. Adv. Anim. Vet. Sci. 10(12), pp. 2533-2537. (Q3-Corresponding Author)
15. Detcharoenyos, N., Pattanapon, N., Petchdee, S. (2022). Management of Spinal Osteochondroma in Young Golden Retriever Dog. Adv. Anim. Vet. Sci. 10(7), 1513–1517. (Q3-Corresponding Author)
16. Chanda, M., Petchdee, S. (2022). Cardiac morphology changes in horses as a response to various types of sports. J. Appl. Anim. Res. 50(1), 453-459. (Q1-Corresponding Author)
17. Sukumolanan, P., Demeekul, K., & Petchdee, S. (2022). Development of a Loop-Mediated Isothermal Amplification Assay Coupled With a Lateral Flow Dipstick Test for Detection of Myosin Binding Protein C3 A31P Mutation in Maine Coon Cats. Frontiers in Veterinary Science, 9, 819694. https://doi.org/10.3389/fvets.2022.819694. (Q1-Corresponding Author)
18. Sukumolanan, P., & Petchdee, S. (2022). Prevalence of cardiac myosin-binding protein C3 mutations in Maine Coon cats with hypertrophic cardiomyopathy. Veterinary world, 15(2), 502–508. https://doi.org/10.14202/vetworld.2022.502-508. (Q1-Corresponding Author)
19. Petchdee, S., Yalong, M., Kaewnet, M., Ithisariyanont, B., & Padawong, T. (2022). Assessment of Right Ventricular Function, Blood Lactate Levels, and Serum Peptidomics Profiles Associated With Mitral Valve Disease in Dogs. Frontiers in Veterinary Science, 8, 789137. https://doi.org/10.3389/fvets.2021.789137. (Q1-First and Corresponding Author)
Saponins obtained from the sea cucumber Holothuria leucospilota have been widely recognized for their metabolic and cytoprotective properties; however, their influence on cardiovascular structure and function has not been fully clarified. This study investigated the cardioprotective effects of saponin supplement in a high-fat diet rabbit model with renovascular hypertension. Sixteen New Zealand White rabbits were divided into four experimental groups: a normal diet group, a high-fat diet group with partial renal artery ligation, and two treatment groups receiving the same high-fat diet and ligation combined with either low-dose or high-dose saponin supplementation. Hypertension was established through partial constriction of the left renal artery.
Physiological and metabolic assessments, including body weight, blood biochemical profiles, arterial pressure, and cardiac structure and function, were conducted at baseline and during the experimental period. Rabbits receiving saponin supplementation demonstrated an improvement in metabolic indices, with significant reductions in circulating glucose, triglycerides, and cholesterol levels compared with untreated hypertensive animals. In addition, mean arterial pressure was substantially reduced in both saponin-treated groups. Cardiac imaging revealed a clear attenuation of left ventricular wall thickening, indicating suppression of hypertensive cardiac remodeling.
These findings provide evidence that saponins derived from Holothuria leucospilota exert protective effects on the heart under conditions of diet-induced metabolic stress and elevated blood pressure. The combined improvement in metabolic status, blood pressure regulation, and cardiac structure suggests that this marine-derived compound may represent a promising natural adjunct strategy for reducing cardiovascular risk associated with obesity and hypertension.
References:
1. Hossain A, Dave D, Shahidi F. Northern Sea Cucumber (Cucumaria frondosa): A Potential Candidate for Functional Food, Nutraceutical, and Pharmaceutical Sector. Mar Drugs. 2020;18(5):274. Published 2020 May 22. doi:10.3390/md18050274.
2. Hossain A, Senadheera TRL, Dave D, Shahidi F. Phenolic profiles of Atlantic sea cucumber (Cucumaria frondosa) tentacles and their biological properties. Food Res Int. 2023;163:112262. doi:10.1016/j.foodres.2022.112262
3. Hossain A, Dave D, Shahidi F. Antioxidant Potential of Sea Cucumbers and Their Beneficial Effects on Human Health. Mar Drugs. 2022;20(8):521. Published 2022 Aug 15. doi:10.3390/md20080521
4. Fagbohun OF, Joseph JS, Oriyomi OV, Rupasinghe HPV. Saponins of North Atlantic Sea Cucumber: Chemistry, Health Benefits, and Future Prospectives. Mar Drugs. 2023;21(5):262. Published 2023 Apr 23. doi:10.3390/md21050262
5. Senadheera TRL, Hossain A, Dave D, Shahidi F. Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa). Molecules. 2023;28(13):5263. Published 2023 Jul 7. doi:10.3390/molecules28135263